49) Hurben, AK; Zhang Q; Galligan, JJ; Tretyakova, N; Erber, L. “Endogenous Cellular Metabolite Methylglyoxal Induces DNA-Protein Cross-Links in Living Cells” ACS Chem Biol 2024 Jun 21 (PMID: 38752800)

48) Trujillo, MN; Jennings, EQ; Hoffman, EA; Zhang, H; Phoebe, AM; Mastin, GE; Kitamura, N; Reisz, JA; Megill, E; Kantner, D; Marcinkiewicz, MM; Twardy, SM; Lebario, F; Chapman, E; McCullough, RL; D’Alessandro, A; Snyder, NW; Cusanovich, DA; Galligan, JJ. “Lactoylglutathione promotes inflammatory signaling in macrophages” Mol Metabolism. 2024 Sep 20 (PMID: 38307385)

47) Zhang, H; Mulqueen, RM; Iannuzo, N; Farrera, DO; Polverino, P; Galligan, JJ; Ledford, JG; Adey, AC; Cusanovich, DA. “txci-ATAC-seq, a massive-scale single-cell technique to profile chromatin accessibility” Genome Biol 2024 Mar 22 (PMID: 38519979)

46) Shanmugam, MM; Chaudhuri, J; Sellegounder, D; Sahu, AK; Guha, S; Chamoli, M; Hodge, B; Bose, N; Roberts, C; Farrera, DO; Gordon Lithgow, G; Sarpong, R; Galligan, JJ; Kapahi, P. “Methylglyoxal-derived hydroimidazolone, MG-H1, increases food intake by altering tyramine signaling via the GATA transcription factor ELT-3 in Caenorhabditis elegans” eLife. 2023 Sep 20 (PMID: 37728328)

45) Kitamura, N; Galligan, JJ. “A global view of the human post-translational modification landscape” Biochem J 2023 Aug 30 (PMID: 37610048)

44) Trujillo, MN; Galligan, JJ. “Reconsidering the role of protein glycation in disease” Nat Chem Biol 2023 Jul 10 (PMID: 37430113)

43) Farrera, D; Galligan, JJ. “The human glyoxalase gene family in health and disease” Chem Res Toxicol 2022 Sep 1 (PMID: 36048613)

42) McGinnis, CD; Jennings, EQ; Harris, PS; Galligan, JJ; Fritz, KS. “Biochemical mechanisms of sirtuin-directed protein acylation in hepatic pathologies of mitochondrial dysfunction” Cells 2022 Jun 28 (PMID: 35805129)

41) Zhang, H; Rice, ME; Alvin, JW; Farrera-Gaffney, D; Galligan, JJ; Johnson, MDL; Cusanovich, DA. “Extensive evaluation of ATAC-seq protocols for native or formaldehyde-fixed nuclei” BMC Genomics. 2022 Mar 17 (PMID: 35296236

40) Ray, DM; Jennings, EQ; Maksimovic, I; Chai, X; Galligan, JJ*; Zheng, Q*; David, Y*. “Chemical labeling and enrichment of histone glyoxal adducts” ACS Chem Biol. 2022 Mar 16 (PMID:35294181)  *Co-corresponding author

39) Dodson, M; Dai, W; Anandhan, A; Schmidlin, CJ; Liu, P; Wilson, NC; Wei, Y; Kitamura, N; Galligan, JJ; Ooi, A; Chapman, E; Zhang, DD. “CHML is an NRF2 target gene that regulates mTOR function” Mol Oncol 2022 Feb 20 (PMID: 35184380)

38) Jennings, EQ; Fritz, KS; Galligan, JJ. “Biochemical genesis of enzymatic and non-enzymatic post-translational modifications” Mol Aspects Med 2021 Nov 24 (PMID: 34838336)

37) Miller, S; Jilek, J; McGrath, ME; Hau, R; Jennings, EQ; Galligan, JJ; Wright, S; Cherrington, NJ. “Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters” Pharmacol Res Perspect. 2021 Aug 9 (PMID: 34288585)

36) Khadka, S; Arthur, S; Barekatain, Y; Behr, E; Washington, M; Ackroyd, J; Crowley, K; Suriyamongkol, P; Lin, Y; Pham, C; Zielinski, R; Trujillo, MN; Galligan, JJ; Georgiou, DK; Asara, J; Muller, FL. “Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma” Cancer and Metabolism. 2021 Jun 25 16 (PMID: 34172075)

35) Jennings, EQ; Ray, JD; Zerio, CJ; Trujillo, MN; McDonald, DM; Chapman, E; Spiegel, DA; Galligan JJ. “Sirtuin 2 Regulates Protein LactoylLys Modifications” ChemBioChem. 2021, Mar 16 (PMID: 33725370)

34) Marentette, JO; Anderson, CC; Prutton, KM; Jennings, EQ; Rauniyar, AK; Galligan, JJ; Roede, JR. “Trisomy 21 Impairs PGE2 Production in Dermal Fibroblasts” Prostaglandins and Other Lipid Mediat. 2021, Jan 5 (PMID: 33418267)

33) Miller, S; Zhang, X; Hau, R; Jilek, J; Jennings, EQ; Galligan, JJ; Foil, D; Zorn, K; Ekins, S; Wright, S; Cherrington, NJ. “Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling" Mol Pharmacol. 2020 Dec 1 (PMID: 33262250)

32) Perer, J; Jandova, J; Fimbres, J; Jennings, EQ; Galligan, JJ; Hua, A; Wondrak, GT. “The Sunless Tanning Agent Dihydroxyacetone Induces Stress Response Gene Expression and Signaling in Cultured Human Keratinocytes and Reconstructed Epidermis” Redox Biol 2020 May 29;36:101594 (PMID: 32506039)

31) Maksimovic, I; Zheng, Q; Trujillo, MN; Galligan, JJ; David, Y. “An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation” J Am Chem Soc, 2020 May 10 (PMID: 32390412)

30) Nam, M; Smith, AJO; Pantcheva, MB; Park, KU; Brzezinski Iv, JA; Galligan, JJ; Fritz, KS; Wormstone, IM; Nagaraj, RH. “Aspirin Inhibits TGFβ2-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells: Selective Acetylation of K56 and K122 in Histone H3” Biochem J, 2019 Dec 9 (PMID: 31815277)

29) Gaffney, DO*; Jennings, EQ*; Anderson, CC; Marentette, JO; Shi T; Oxvig, AS; Streeter, MD; Johannsen, M; Spiegel, DA; Chapman, D; Roede, JR; Galligan, JJ.“Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes” Cell Chem Biol, 2019 Nov 22 (PMID: 31767537)

28) Galligan JJ; “Chromatin Modifications in Toxicology” Chem Res Toxicol 2018 Dec 6 (PMID: 30521321)

27) Sibbersen, C; Oxvig, AS; Olesen, SB; Galligan, JJ; Jørgensen, KA; Palmfeldt, J; Johannsen, M. “Profiling of Methylglyoxal Blood Metabolism and Advanced Glycation End-Product Proteome Using a Chemical Probe” ACS Chem Biol, 2018 Dec 3 (PMID: 30508371)

26) Wepy, JA; Galligan, JJ; Kingsley, PJ; Xu, S; Goodman, MC; Tallman, KA; Rouzer, CA; Marnett, LJ. “Lysophospholipases Cooperate to Mediate Lipid Homeostasis and Lysophospholipid Signaling” J Lipid Res, 2018 Nov 27 (PMID: 30482805)

25) Galligan, JJ; Wepy, JA; Streeter, MD; Kingsley, PJ; Mitchener, MM; Wauchope, OR; Rose, KL; Wang, T; Spiegel, DA; Marnett, LJ. “Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks” Proceedings of the National Academy of Sciences 2018 Aug 27 (PMID: 30150385)

24) Wauchope, OR; Mitchener, MM; Beavers, WN; Galligan, JJ; Camarillo, JM; Sanders, WD; Kingsley, PJ; Shim, H; Blackwell, T; Luong, T; deCaestecker, M; Fessel, JP; Marnett, LJ. “Oxidative Stress Increases M1dG, a Major Peroxidation-Derived DNA Adduct, in Mitochondrial DNA” Nuc Acids Res 2018 Feb 9 (PMID: 29438559)

23) Beavers, WN; Rose, KL; Galligan, JJ; Mitchener, MM; Tallman, KA; Lamberson, CR; Wang, X; Hill, S; Ivanova, P; Brown, HA; Zhang, B; Porter, NA; Marnett, LJ. “Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as Triggers and Targets” ACS Chem Biol 2017 Jun 14 (PMID: 28613820)

22) Galligan, JJ; Kingsley, PJ; Wauchope, OR; Mitchener, MM; Camarillo, JM; Wepy, JA; Harris, PS; Fritz, KS; Marnett, LJ. “Quantitative Analysis and Discovery of Lysine and Arginine Modifications (QuARKMod)” Anal Chem 2017 Jan 17 (PMID: 27982582)

21) Galligan JJ; Marnett, LJ; “Histone Adduction and its Functional Impact on Epigenetics” Chem Res Toxicol 2016 Dec 8 (PMID: 27930886)

20) Escher, BI; Hackermüller, J; Polte, T; Scholz, S; Aigner, A; Altenburger, R; Böhme, A; Bopp, SK; Brack, W; Busch, W; Chadeau-Hyamd, C; Covaci, A; Eisenträger, A; Galligan, JJ; Garcia-Reyero, N; Hartung, T; Hein, M; Herberth, G; Jahnke, A; Kleinjans, J; Klüver, N; Krauss, M; Lamoree, M; Lehmann, I; Luckenbach, T; Miller, GW; Müller, A; Phillips, DH; Reemtsma, T; Rolle-Kampczyk, U; Schüürmann, G; Schwikowski, B; Tan, YM; Trump, S; Walter-Rohde, S; Wambaugh, JF. “From the exposome to mechanistic understanding of chemical-induced adverse effects” Environ Int 2016 Dec 8 (PMID: 27939949)

19) Mont, S; Davies, SS; Roberts, LJ; Mernaugh, RL; McDonald, WH; Segal, BH; Zackert, W; Kropski, JA; Blackwell, TS; Sekhar, KR; Galligan, JJ; Massion, PP; Marnett, LJ; Travis, EL; Freeman, ML. “Accumulation of Isolevuglandin-Modified Protein in Normal and Fibrotic Lung” Sci Reports 2016 Apr 27 (PMID: 27118599)

18) Camarillo, JM; Rose, KL; Galligan, JJ; Marnett, LJ. “Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression” Chem Res Toxicol 2016 Mar 11 (PMID: 26910110)

17) Wauchope, OR; Beavers, WN; Galligan, JJ; Mitchener, MM; Kingsley, PJ; Marnett, LJ. “Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG in the Genome” Chem Res Toxicol 2015 Dec 21 (PMID: 26469224)

16) Aluise, CD; Camarillo, JM; Shimozu, Y; Galligan, JJ; Rose, KL; Tallman, KA; Marnett, LJ. “Site-Specific, Intramolecular Cross-Linking of Pin1 Active Site Residues by the Lipid Electrophile 4-oxo-2-nonenal” Chem Res Toxicol 2015 Apr 20 (PMID: 25739016)

15) Kudalkar, SN; Nikas, SP; Kingsley, P; Xu, S; Galligan, JJ; Rouzer, CA; Ji, L; Eno, MR; Makriyannis, A; Marnett, LJ. “13-Methylarachidonic Acid is a Positive Allosteric Modulator of Endocannabinoid Oxygenation by Cyclooxygenase-2” J Biol Chem 2015 Mar 20 (PMID: 25648895)

14) Shuck, SC; Wauchope, OR; Rose, KL; Kingsley, PJ; Rouzer, CA; Shell, SM; Sugitani, N; Chazin, WJ; Zagol-Ikapitte, I; Boutaud, O; Oates, JA; Galligan, JJ; Beavers, WN; Marnett, LJ. “Protein Modification by Adenine Propenal” Chem Res Toxicol 2014 Oct 20 (PMID: 25211669)

13) Galligan, JJ; Rose, KL; Beavers, WN; Hill, S; Tallman, KA; Tansey, WP; Marnett, LJ. “Stable Histone Adduction by 4-oxo-2-nonenal: A Potential Link Between Oxidative Stress and Epigenetics” J Am Chem Soc 2014 Aug 27 (PMID: 25099620)

12) Shearn CT; Fritz, KS; Shearn, AH; Saba, LM; Mercer, KE; Engi, B; Galligan, JJ; Zimniak, P; Orlicky, DJ; Ronis, M; Petersen, DR. “Deletion of GSTA4-4 Results in Increased Mitochondrial Post-translational Modification of Proteins by Reactive Aldehydes Following Chronic Ethanol Consumption in Mice” Redox Biol 2015 Nov 27 (PMID: 26654979)

11) Galligan, JJ; Fritz, KS; Backos, DS; Shearn, CT; Smathers, RL; Jiang, H; MacLean, KN; Reigan, P; Petersen, DR. “Oxidative Stress Mediated Aldehyde Adduction of Grp78 in a Mouse Model of Alcoholic Liver Disease: Functional Independence of ATPase Activity and Chaperone Function” Free Radical Biol Med 2014 Aug (PMID: 24924946)

10) Smathers, RL; Galligan, JJ; Shearn CT; Fritz, KS; Mercer, K; Ronis, M; Orlicky, DJ; Davidson, NO; Petersen, DR. “Susceptibility of LFABP -/- Mice to Oxidative Stress in Early-Stage Alcoholic Liver” J Lipid Res 2013 Jul 28 (PMID: 23359610)

9) Galligan, JJ; Smathers, RL; Shearn CT; Fritz, KS; Backos, DS; Jiang, H; Franklin, CC; Orlicky, DJ; MacLean, KN; Petersen, DR. “Oxidative Stress and the ER Stress Response in a Timecourse Model for Alcoholic Liver Disease” J Tox 2012 Jul 5 (PMID: 22829816)

8) Galligan, JJ; Petersen, DR. “The Human Protein Disulfide Isomerase (PDI) Gene Family” Hum Genomics 2012 Jul 5 (PMID: 23245351)

7) Smathers, RL; Fritz, KS; Galligan, JJ; Shearn, CT; Reigan, P; Marks, MJ; Petersen, DR. “Characterization of 4-HNE Modified L-FABP Reveals Alterations in Structural and Functional Dynamics” PLoS One 2012 Jun 6 (PMID: 22701647)

6) Galligan, JJ; Smathers, RL; Fritz, KS; Epperson, LE; Hunter, LE; Petersen, DR. “Protein Carbonylation in a Murine Model for Early Alcoholic Liver Disease” Chem Res Toxicol 2012 Apr 13 (PMID: 22502949)

5) Fritz, KS; Galligan, JJ; Hirschey, MD; Verdin, E; Petersen, DR. “Mitochondrial Acetylproteomic Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice” J Proteome Res 2012 Feb 6 (PMID: 22309199)

4) Shearn, CT; Smathers, RL; Stewart, BJ; Fritz, KS; Galligan, JJ; Hail, N; Petersen, DR. “Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Inhibition by 4-Hydroxynonenal Leads to Increased AKT Activation in Hepatocytes” Mol Pharmacol 2011 Jun (PMID: 21415306)

3) Smathers, RL; Galligan, JJ; Stewart, BJ; Petersen, DR. “Overview of Lipid Peroxidation Products and Hepatic Protein Modification in Alcoholic Liver Disease” Chem Biol Interact 2011 Jun 30 (PMID: 21354120)

2) Fritz, KS; Galligan, JJ; Smathers, RL; Roede, JR, Shearn, CT; Reigan P; Petersen, DR. “4-Hydroxynonenal Inhibits SIRT3 Via Thiol-Specific Modification” Chem Res Toxicol 2011 May 16 (PMID: 21449565)

1) Galligan, JJ; Fritz, KS; Tipney, H; Smathers, RL; Roede, JR; Shearn, CT; Hunter, LE; Petersen, DR. “Profiling Impaired Hepatic Endoplasmic Reticulum Glycosylation as a Consequence of Ethanol Ingestion” J Proteome Res 2011 Apr 1 (PMID: 21319786)